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Product Name: Hesperidin

Synonym:  Hesperetin-7-rhamnoglucoside, Cirmtin, Hesperetin-7-rutinoside


CAS: 520-26-3 

Chemical Name: (2S)-7-[[6-O-(6-Deoxy--L-mannopyranosyl)--D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Molecular Formula: C28H34O15

Molecular Weight: 610.55

Botanical Source: Rubiaceae Galium mollugo L. Aerial part. [1] rutaceous citrus medica L. var. sarcodatylis (Noot.) swingle fruit [2] C. tankan hayata fruit [3] poncirus trifoliate L. raf. Fruit [4] Citrus lemon burm. Fruit [5] C. limonia osbeck peel, C.medica L. mature fruit [6] crucifer capsella bursa-pastoris L. medic, full plant with root [7].

Physical Property: thin dendritic-needle-crystal ( PH6-7 precipitation incomes). M.P.: 258-262℃ (soften at 250℃). [α]20D-76℃(C=2,pyridine). 1g soluble in 50L water, soluble in dimethyl formamide and formamide at 60℃, slightly soluble in methanol and heat glacial acetic acid, practically insoluble in acetone, benzene and chloroform, freely soluble in dilute alkali and pyridine.


   -   Anti-inflammatory: take cavy as experimental animal, hesperidin has an improvement effect on eye conjunctival intravascular coagulation of blood cells caused by vitamin C deficiency in cavy and low resistibility of capillary. In other words, hesperidin can enhance the effect of vitamin C. However, it is reported that hesperidin can reduce the coagulation of blood cells. Mixing hespridin with hromobogenic or atherosclerosis to feed cavy, it will prolong survival time of cavy. What’s more, it can promote the growth rate of cavy in vitamin C deficiency by increasing the content of vitamin C in adrenal gland, spleen and white blood cells.

   -   Anti-virus: put fibro cells of cavy into 200ug/ml hesperidin for hatching in advance before adding vesicular stomatitis virus, with such handling which can protect cells from virus for about 24hours. Similarly, hatching Hela cells in the same way can prevent influenza virus infection. However, the anti-virus activity of hesperidin can be cancelled by hyaluronidase. 

   -   Others: frostbite prevention and rat-eyes-lens-aldehyde reductase prevention.

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