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Diacerein appears to yellow needle-like crystallites when the solvent is methanol, and was brown-yellow needle-like crystallites in acetone. Diacerein's melting point is 237-238℃, boiling point is 631.5℃ at 760 mmHg, flash point is 231.8℃. Diacerein's density is 1.491g/cm3. Diacerein can easily dissolve in dimethyl sulfoxide, dimethyl acetamide, but can't dissolve in water, methanol and chloroform. Diacerein is anti inflammation and analgesic drugs, for the treatment of osteoarthritis and osteoarthritis. This product has almost no gastrointestinal side effects and is well tolerated.
1) Diacerein has the role of delaying the deterioration processes of osteoarthritis.
2) Diacerein can exert effects of anti-inflammatory and anti-febrile by combining with oxygen free radical and inactivating it.
3) Diacerein could form water-soluble chelating(EGTA and EDTA Cu) of resisting rheumatism with calcium and copperions.
Diacerein can be widely used for the intermediates of pharmaceutical and chemical industry.