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SERENOA REPENS L.E. (SABALSELECT INDENA)

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PRODUCT SERENOA REPENS LIPOSOLUBLE EXTRACT (SABALSELECT INDENA)

INCI NAME Serenoa serrulata Fruit Extract

BOTANICAL NAME Serenoa repens (Bartr.) Small

BOTANIC FAMILY Arecaceae

CAS NUMBER 84604-15-9 o 90106-85-7

EINECS/ELINCS NUMBER 290-312-5 o 283-292-4

OTHER NAMES Sabal, Saw palmetto

Sabal serrulata

ORIGIN OF THE PLANT Spontaneous

ORIGIN OF RAW MATERIAL USA (FL-GA)

PART OF PLANT USED Fruit. The fruit of Serenoa repens used by Indena complies with Ph. Eur V ed.

HARVESTING August-October

TYPE OF PRODUCT AND USE Food and cosmetic grade

DESCRIPTION Standardized liposoluble extract obtained by supercritical CO2 extraction from ripe fruits of Serenoa repens

IDENTIFICATION OF THE HERBAL SUBSTANCE Botanical identification: Ph. Eur. monograph. ("Saw Palmetto fruits"); chemical identification: Ph. Eur. monograph. ("Saw Palmetto fruits")

COMPOSITION Total fatty acids: 93,5%, of which: 59,8% are saturated fatty acids (caproic acid: 1,5%; caprylic acid: 2,3%; capric acid: 2,5%; lauric acid: 30,2%; myristic acid: 12,0%; palmitic acid: 9,5%; stearic acid: 1,8%) and 33,7% of unsaturated fatty acids (oleic acid: 28,5%; linoleic acid: 4,6%; linolenic acid: 0,6%); fatty alcohols: 0,20% (hexacosanol: 0,017%; octacosanol: 0,146%; tetracosanol: 0,004%; triacontanol: 0,033%); Sterols: 0,32% (Campesterol: 0,07%; Stigmasterol: 0,03%; beta-sitosterol: 0,22%). The chemical composition of Sabalselect is determined through a validated GLC method

ALLERGENS Free from food allergens (Dir. 2000/13/EC and subsequent amendments)

STORAGE Store in well closed containers, away from light, heat and moisture

STABILITY Turbidity can be observed at temperatures below 20}C

PROPERTIES Sabalselect act specifically at the level of prostate tissue, without causing systemic changes in hormone levels. The extract, due to its complex composition, has multiple mechanisms of action: inhibition of the enzyme 5-alpha-reductase inhibitors (anti-androgen), blocking cyclooxygenase and lipoxygenase (anti-inflammatory), inhibit the production of leukotrienes by chemotactic part of the inflammatory cells, reduction of the proliferative response of the prostate to growth factors, inhibitory effect on nuclear estrogen receptors, interference with the action of prolactin, antagonistic action on alpha-adrenergic; were also described spasmolytic activity and muscle-relaxants

HEALTHY AIMS Useful in the treatment of urological disorders

RECOMMENDED DOSAGE 160 mg, 2 times/day or 320 mg in a single dose